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Outlook 2010 will not close

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Hello,

    This issue has been affecting a few of my users for a few weeks and I am completely stumped as to what could be causing this.  Outlook 2010 is installed and users have PST files mapped to a network share.  When they try to access an email in the PST that has a large attachment or tries to forward an email with or without an attachment, Outlook hangs and says that it is Not Responding.  When I try to click on th X to close the window it turns a translucent white and I can't do anything.  I finally get into Task Manger to end the OUTLOOK.EXE process but there are two of them listed.  I can close one and not the other.  As a matter of fact, when I try to close the second one a dialog box opens that says Access Denied and all I can do is close the box.  The only way I can clear it out is by shutting down the PC, turning it back on and logging the user in again.  The users have 500MB mailboxes and PST files between 2 and 3 GB.  I have tried deleteing and recreating both Windows and Outllok profiles but the issues contniues to return.

Thank you for any help you can provide!


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